수면정신생리

수면정신생리 (5권2호 177-184)

The influence of sleep and sleep apnea on memory function

수면 무호흡과 수면이 기억기능에 미치는 영향

Lee, Sung-Hoon;Lee, Na-Young;Park, Yun-Jo;Jon, Duk-In;

Yonjung Brain Function and Sleep Research Center;Yonjung Brain Function and Sleep Research Center;Yonjung Brain Function and Sleep Research Center;Department of Psychiatry, Yonsei University College of Medicine;

Abstract

Objectives : Disturbance of sleep with or without sleep apnea may impair the memory function. Sleep deficiency, sleepiness, sleep apnea and emotional problem in sleep disorders can induce an impairment of memory function. Methods : In this study, the polysomnographies were administered to 58 sleep apnea patients and 38 sleep disorder patients without sleep apnea. Their clinical symptoms were quantitatively evaluated. Short term and long term memory were evaluated before and after polysom no graphy with Digit symbol test and Rey-Osterrieth complex figure test. And correlations among various sleep, repiratory and clinical variables were statistically studied in order to explore which variables may influence on memory function. Results and Conclusions : Results are as follows. Depth of sleep cis positively correlated with memory function. As sleep apnea increases and average saturation of blood oxygen decreases, memory function is more impaired. Emotional depression, high blood pressure, obesity or alcohol impaired memory function. However, daytime sleepiness was not significantly correlated with memory function. The possible mechanisms how above factors influence on the memory function were discussed.

Keywords

sleep;sleep apnea;memory function;