수면정신생리

수면정신생리 (25권1호 5-8)

Updates on the Treatment of Restless Legs Syndrome

하지불안증후군 치료의 최신지견

Kang, Seung-Gul;

Department of Psychiatry, Gil Medical Center, Gachon University, College of Medicine;

DOI : http://dx.doi.org/10.14401/KASMED.2018.25.1.5

Abstract

Restless legs syndrome (RLS) is a sleep disorder characterized by an urge to move the legs or arms and uncomfortable paresthesia in the legs. Treatment of RLS can be various depending on the causes, severity, and frequency of the symptoms. In the case of secondary RLS, it is important to identify and manage the cause of RLS. Dopamine agonists have been used as firstline treatments for primary RLS treatment. However, due to augmentation, which is a common side effect of dopamine agonists, recent treatment guidelines are changing to prefer to anticonvulsants such as pregabalin and gabapentin. Iron, opioid, or benzodiazepine may be used when anticonvulsants or dopamine agonists are not adequately treated. Because RLS is a chronic disease, it is essential to establish a long-term treatment plan considering both efficacy and side effects.

Keywords

Anticonvulsant;Augmentation;Dopamine agonist;Restless legs syndrome;Treatment;