수면정신생리

수면정신생리 (3권1호 68-78)

A Study on the Clinical Usefulness of MMSE and BCRS for Cognitive Function Test in Patients with Non-Traumatic Subcortical Cerebrovascular Disease

비외상성 피질하 뇌혈관질환 환자에서 인지평가도구로서 정신상태소검사(MMSE)와 간이인지평가척도(BCRS)의 임상적 유용성에 대한 연구

Choi, Hong;Lee, Young-Ho;Choi, Young-Hee;Ko, Dae-Kwan;Chung, Young-Cho;Park, Byoung-Kwan;Kim, Soo-Ji;Chung, Sook-Haui;Ko, Byoung-Hee;Song, Il-Byoung;Park, Kun-Woo;Lee, Dae-Hie;

Department of Neuropsychiatry, College of Medicine, Inje University, Seoul Paik Hospital;Department of Neuropsychiatry, College of Medicine, Inje University, Seoul Paik Hospital;Department of Neuropsychiatry, College of Medicine, Inje University, Seoul Paik Hospital;Department of Neuropsychiatry, College of Medicine, Inje University, Seoul Paik Hospital;Department of Neuropsychiatry, College of Medicine, Inje University, Seoul Paik Hospital;Korea Institute for Psychological Consulting;Department of Psychology, College of Medicine, Inje University, Seoul Paik Hospital;Korea Institute for Psychological Consulting;Department of Constitutional Medicine, College of Oriental Medicine, Kyung Hee University, Oriental Medicine Hospital;Department of Constitutional Medicine, College of Oriental Medicine, Kyung Hee University, Oriental Medicine Hospital;Department of Neurology, College of Medicine, Korea University, Anam Hospital;Department of Neurology, College of Medicine, Korea University, Anam Hospital;

Abstract

Objective : The Mini-Mental State Examination(MMSE) and Brief Cognitive Rating Scale(BCRS) are frequently using screening tests fur evaluating the cognitive function in clinical practice and research. The authors tried to evaluate the clinical usefulness of these tests for the patients with non-traumatic subcortical cerebrovascular disease. Method : We administered the MMSE and BCRS to 85 patients and 195 normal control group. In order to compare the test results according to the lesion site, we divided patients into left sided lesion group(21 patients), right sided lesion group(31 patients) and both sided lesion group(13 patients). Their cognitive function was evaluated by the BNA and daily living functional activity was examined by the IADLs(Instrumental Activities of Daily Living Scale)and GERRI(Geriatric Evaluation by Relative''s Rating Instrument). Results : The results are as follows : 1) In the BNA, the patients scored significantly lower than control group at all items(except Right-Left Orientation and Motor Impersistence), but there were no difference in the MMSE(total score and all 5 items), and only 2 items(recent memory and self-care) were significantly different between two groups in the BCRS. 2) In the comparison by lateralization, there were significant differences among three groups at 3 items(Left Tactile Form Perception, Left Finger Localization and Right Finger Localization) in the BNA. But, there were no difference in the MMSE and BCRS. 3) In the correlation between daily living functioning and the MMSE/BCRS, control group showed no relation(except item of cognitive functioning), but patient group was significantly correlated with 3 items(social functioning, instrumental activities of daily living and cognitive functioning). Conclusions : These findings suggest that MMSE and BCRS are not useful as the test for cognitive function and discrimination of lateralization in patients with non-traumatic subcortical cerebrovascular disease. However, scores of these tests may be related with the functional level(such as daily living function) of patients.

Keywords

Non-traumatic subcortical cerebrovascular disease;MMSE;BCRS;Clinical usefulness;